Pyrrolobenzodiazepines and related systems. 2. Synthesis and biological properties of isonoraptazepine derivatives

DOI: 10.1021/jm00102a004

Source and publish data:

Journal of Medicinal Chemistry p. 4533 - 4541 (1992)

Update date:2022-07-30

Topics:

Authors:

Massa Massa

Artico Artico

Mai Mai

Corelli Corelli

Botta Botta

Tafi Tafi

Pantaleoni

Giorgi Giorgi

Coppolino

Cagnotto

Skorupska

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Article abstract of DOI:10.1021/jm00102a004

The synthesis of some derivatives and analogues of 12,13,14,14a- tetrahydro-9H,11H-pyrazino-[2,1-c]pyrrolo[1,2-a][1,4]benzodiazepine (isonoraptazepine) is reported. The new derivatives have been subjected to pharmacological tests for evaluation of antidep

Full text of DOI:10.1021/jm00102a004

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Product name:13-[(4-chlorophenyl)carbonyl]-12,13,14,14a-tetrahydro-9H,11H-pyrazino[2,1-c]pyrrolo[1,2-a][1,4]benzodiazepine

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