Preparation of (22S)- and (22R)-24-homo-26,26,26,27,27,27-hexafluoro-1,22,25-trihydroxy-24-yne-v itamin D3

DOI: 10.1248/cpb.40.1647

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1647 - 1649 (1992)

Update date:2022-08-04

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Authors:

Ohira Ohira

Taguchi Taguchi

Iseki Iseki

Kobayashi

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Article abstract of DOI:10.1248/cpb.40.1647

A convergent synthesis of the titled fluorinated analogs of the 1,25-dihydroxyvitamin D₃, which modulates butyrate-induced differentiation of HT-29 human colonic carcinoma cells with very little effect on bone calcium mobilization, is reported.

Full text of DOI:10.1248/cpb.40.1647

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