Synthesis of Four Stereoisomeric Tetrose Derivatives from Propargyl Alcohol. One-carbon Homologation of Vinylsilanes via α,β-Epoxy Silanes

Article abstract of DOI:10.1021/jo00050a041

Silicon-mediated synthesis of stereomeric tetroses 1, 2, 3, and 4, from propargyl alcohol is described.An allylic alcohol bearing the trimethylsilyl group in the γ position, rac-9b, was subjected to the Sharpless kinetic resolution to give (2S)-9b and the