Stereospecific Synthesis of (2S,4R)--Leucine

DOI: 10.1016/S0040-4039(00)61328-X

Source and publish data:

Tetrahedron Letters p. 4617 - 4620 (1992)

Update date:2022-08-04

Topics:

Authors:

August, Ryan A.

Khan, Jeffrey A.

Moody, Claire M.

Young, Douglas W.

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Article abstract of DOI:10.1016/S0040-4039(00)61328-X

The first fully stereospecific synthesis of a sample of the amino acid (2S)-leucine labelled in only one of the diastereotopic methyl groups has been achieved using (2S)-pyroglutamic acid as a chiral template. Key Words: leucine; stereospecific synthesis; amino acid; isotopic labelling; bio-organic

Full text of DOI:10.1016/S0040-4039(00)61328-X

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Product name:tert-butyl (2S,4S)-N-(tert-butoxycarbonyl)-5-hydroxy-<5,5-(2)H2>leucine

Cas No:144331-23-7

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