
Tetrahedron Letters p. 4617 - 4620 (1992)
Update date:2022-08-04
Topics:
August, Ryan A.
Khan, Jeffrey A.
Moody, Claire M.
Young, Douglas W.
The first fully stereospecific synthesis of a sample of the amino acid (2S)-leucine labelled in only one of the diastereotopic methyl groups has been achieved using (2S)-pyroglutamic acid as a chiral template. Key Words: leucine; stereospecific synthesis; amino acid; isotopic labelling; bio-organic
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Doi:10.1002/anie.201603232
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