Synthesis of N-demethyl-N-substituted-14-hydroxycodeine and morphine derivatives

Article abstract of DOI:10.1080/00397919208021649

A few representatives (1b-d) of a novel group of structurally related morphine-antagonist compounds have been prepared in stereochemically homogeneous form. The employed procedures involve O-demethylation either of the corresponding codeine derivatives 2b

Full text of DOI:10.1080/00397919208021649

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Synthetic Communications: An
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Synthesis of N-Demethyl-N-
Substituted-14-Hydroxycodeine
and Morphine Derivatives+
Sándor Hosztafi a , Csaba Simon a & Sándor Makleit b
a Alkaloida Pharmaceutical Works Rt., H-4440,
Tiszavasvári, Hungary
b Department of Organic Chemistry, L. Kossuth
University, H-4010, Debrecen, Hungary
Available online: 23 Sep 2006
To cite this article: Sándor Hosztafi, Csaba Simon & Sándor Makleit (1992): Synthesis
of N-Demethyl-N-Substituted-14-Hydroxycodeine and Morphine Derivatives+ ,
Synthetic Communications: An International Journal for Rapid Communication of
Synthetic Organic Chemistry, 22:17, 2527-2541
To link to this article: http://dx.doi.org/10.1080/00397919208021649
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