On the stereoselectivity of the reaction of N-(9-phenylfluoren-9-yl)aspartate enolates with electrophiles. Synthesis of enantiomerically pure 3-hydroxy-, 3-amino-, and 3-hydroxy-3-methylaspartates

Article abstract of DOI:10.1021/jo00104a019

We have developed efficient and stereoselective preparations of enantiomerically pure (3R)- and (3S)-N-Pf-3-hydroxy- and N-Pf-3-aminoaspartates by reaction of N-Pf-aspartate enolates with electrophilic hydroxylating or aminating reagents. The stereoselect