Journal of Medicinal Chemistry p. 5182 - 5197 (2013)
Update date:2022-08-15
Topics:
Funke, Mario
Thimm, Dominik
Schiedel, Anke C.
Müller, Christa E.
8-Amido-chromen-4-one-2-carboxylic acid derivatives were identified as novel agonists at the G protein-coupled orphan receptor GPR35. They were characterized by a β-arrestin recruitment assay and optimized to obtain agonists with nanomolar potency for the
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