Tetrahedron p. 5915 - 5932 (1992)
Update date:2022-08-05
Topics:
Kikelj
Kidric
Pristovisek
Pecar
Urleb
Krbavcic
Honig
The preparation of diastereomerically pure immunologically active carbocyclic nor-muramyldipeptide analogues (1'R,2'R)-/(1'S,2'S)-N-[2-(2'-acetylaminocyclohexyloxy)acetyl]-L- alanyl-D-isoglutamine and (1'R,2'R)-/(1'S,2'S)-N-[2-(2'-acetylaminocyclohexyloxy)acetyl]-L- alanyl-D-glutamic acid is described. The title compounds were synthesized using two independent synthetic routes from racemic trans-2-azidocyclohexanol and (1R,2R)-/(1S,2S)-2-aminocyclohexanol, respectively.
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Doi:10.1002/chem.201404516
(2015)Doi:10.1021/ol401537f
(2013)Doi:10.1016/j.bmcl.2014.04.113
(2014)Doi:10.1021/jo400710r
(2013)Doi:10.1016/S0040-4020(01)80475-0
(1992)Doi:10.1016/j.cclet.2013.05.014
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