A concise stereoselective approach to β-Alkylaspartates from β-Lactams via [2 + 2] cycloaddition reaction of ketenes to glyoxylic ester-derived imines

DOI: 10.1016/S0040-4039(00)61295-9

Source and publish data:

Tetrahedron Letters p. 4823 - 4826 (1992)

Update date:2022-09-26

Topics:

Authors:

Palomo, Claudio

Aizpurua, Jesus M.

Ontoria, Jesus M.

Iturburu, Miren

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)61295-9

syn β-Alkyl aspartates were obtained with high stereoselectivities from cis 4-alkoxycarbonyl-β-lactams prepared via [2 + 2] cycloaddition reaction of monoalkylketenes and glyoxalate derived imines.

Full text of DOI:10.1016/S0040-4039(00)61295-9

Products guided by the article

Product name:(2R,3R)-2-Amino-3-benzyl-succinic acid dimethyl ester

Cas No:144452-40-4

R&D Labs maybe for 144452-40-4

Jiangxi Hito Chemical Co., Ltd.

Contact:+86-792-3170318

Address:No. 6, Tianhong Ave., Xinghuo Industry Park, Yongxiu, Jiujiang, Jiangxi, China
Zhengzhou Xinlian Chemical Tech Co. ,Ltd

Contact:0371-65771781 021-52042910

Address:H Part, Building I, No. 700 Gonglu Road, Pudong New Area, Shanghai
Shandong Xiangde Biotechnology Co., Ltd

Contact:+86 -15066639877

Address:Sanba street
Nanjing Fubang Chemical Co.,Ltd

Contact:+86-25-83179199

Address:5F,Tianzheng international plaza,No399 Zhongyang Road ,Nanjing China
Shaanxi Lighte Optoelectronics Material Co., Ltd.

Contact:+86-29-88320728-622/619/620

Address:No.55 INDUSTRY ROAD 2,XI'AN NATIONAL CIVIL AEROSPACE INDUSTRIAL PARK.XI'AN China 710065.

Relevant to this article

The homo-PADAM protocol: Stereoselective and operationally simple synthesis of α-oxo- or α-hydroxy-γ-acylaminoamides and chromanes

Doi:10.1002/chem.201300023
(2013)
Synthesis, quantitative structure-activity relationship and biological evaluation of 1*3*4-oxadiazole derivatives possessing diphenylamine moiety as potential anticancer agents

Doi:10.1248/cpb.c12-00637
(2013)
Enantioselective total syntheses of (+)-gallocatechin, (-)- epigallocatechin, and 8-C-ascorbyl-(-)-epigallocatechin

Doi:10.1002/asia.201201168
(2013)
Methylenepyran based dipolar and quadrupolar dyes: Synthesis, electrochemical and photochemical properties

Doi:10.1016/j.tet.2013.07.066
(2013)
Synthesis and characterization of new heptalenes with extended π-systems attached to them

Doi:10.1002/hlca.201300137
(2013)
Hemiaminals as substrates for sulfur ylides: Direct asymmetric syntheses of functionalised pyrrolidines and piperidines

Doi:10.1039/b602226j
(2006)

Article Doi