A concise stereoselective approach to β-Alkylaspartates from β-Lactams via [2 + 2] cycloaddition reaction of ketenes to glyoxylic ester-derived imines

DOI: 10.1016/S0040-4039(00)61295-9

Source and publish data:

Tetrahedron Letters p. 4823 - 4826 (1992)

Update date:2022-09-26

Topics:

Authors:

Palomo, Claudio

Aizpurua, Jesus M.

Ontoria, Jesus M.

Iturburu, Miren

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Article abstract of DOI:10.1016/S0040-4039(00)61295-9

syn β-Alkyl aspartates were obtained with high stereoselectivities from cis 4-alkoxycarbonyl-β-lactams prepared via [2 + 2] cycloaddition reaction of monoalkylketenes and glyoxalate derived imines.

Full text of DOI:10.1016/S0040-4039(00)61295-9

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