Synthesis, Configuration, and Activity of Isomeric 2-Phenyl-2-(N-piperidinyl)bicyclohexanes at Phencyclidine and ? Binding Sites

DOI: 10.1021/jm00103a008

Source and publish data:

Journal of Medicinal Chemistry p. 4704 - 4712 (1992)

Update date:2022-08-05

Topics:

Authors:

Costa, Brian R. de

Mattson, Mariena V.

George, Clifford

Linders, Joannes T. M.

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Article abstract of DOI:10.1021/jm00103a008

The novel semirigid derivatives (+)-cis-1-<2-phenyl-2-bicyclo<3.1.0>hexyl>piperidine <(+)-8>, its enantiomer (-)-8, and (+/-)-trans-1-<2-phenyl-2-bicyclo<3.1.0>hexyl>piperidine <(+/-)-9> were synthesized as probes to investigate the mode of interaction of

Full text of DOI:10.1021/jm00103a008

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Product name:cis-(1S,2S,5R)-(+)-2-phenyl-2-bicyclo<3.1.0>hexylamine

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