Remote Asymmetric Induction Based on Carbonyl-Ene Reactions with Bishomoallylic Silyl Ether: Dramatic Changeover of Regioselectivity by the Remarkable Siloxy Effect

Article abstract of DOI:10.1021/jo00049a011

A new approach to remote asymmetric induction is described for not only a 1,4- but also a 1,5-relationship, which is based on the carbonyl-ene reactions with chiral bishomoallylic silyl ethers.Silyl ethers, rather than alkyl ethers, exhibit β-regiospecifi