Synthesis of Optically Active α-Alkylidene-β-hydroxy-γ-methylenebutyrolactones. Isoobtusilactones and Isomahubalactones (Isomahubanolide and Isomahubenolide)

DOI: 10.1246/cl.1992.1647

Source and publish data:

Chemistry Letters p. 1647 - 1650 (1992)

Update date:2022-08-04

Topics: Synthesis Optically active Experimental Methylene Butyrolactones

Authors:

Nokami, Junzo

Ohtsuki, Hirotoshi

Sakamoto, Yasuhuko

Mitsuoka, Masayuki

Kunieda, Norio

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Article abstract of DOI:10.1246/cl.1992.1647

The title compounds were prepared via stereoselective aldol reaction of α,β-unsaturated carboxylate α-anion equivalent, derived from optically active α-(arylsulfinyl)carboxylate and bromomagnesium diisopropylamide, with propargyl aldehyde as a key step.

Full text of DOI:10.1246/cl.1992.1647

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