Synthesis and Biological Evaluation of Calothrixins B and their Deoxygenated Analogues

DOI: 10.1021/acs.jmedchem.7b01797

Source and publish data:

Journal of Medicinal Chemistry p. 1285 - 1315 (2018)

Update date:2022-08-15

Topics:

Authors:

Muthu Ramalingam, Bose

Dhatchana Moorthy, Nachiappan

Chowdhury, Somenath Roy

Mageshwaran, Thiyagarajan

Vellaichamy, Elangovan

Saha, Sourav

Ganesan, Karthikeyan

Rajesh, B. Navin

Iqbal, Saleem

Majumder, Hemanta K.

Gunasekaran, Krishnasamy

Siva, Ramamoorthy

Mohanakrishnan, Arasambattu K.

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Article abstract of DOI:10.1021/acs.jmedchem.7b01797

A series of calothrixin B (2) analogues bearing substituents at the 'E' ring and their corresponding deoxygenated quinocarbazoles lacking quinone unit were synthesized. The cytotoxicities of calothrixins 1, 2, and 15b-p and quinocarbazole analogues were i

Full text of DOI:10.1021/acs.jmedchem.7b01797

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