Organic Letters p. 3891 - 3893 (2013)
Update date:2022-08-03
Topics: NMR Characterization Optimization o-quinone methides tetronic acids Michael reactions X-ray studies functional group interconversions Retrosynthetic analysis Scale-up Purification and Isolation Verification
Spence, Justin T. J.
George, Jonathan H.
The total synthesis of ent-penilactone A and penilactone B has been achieved via biomimetic Michael reactions between tetronic acids and o-quinone methides. A five-component cascade reaction between a tetronic acid, formaldehyde, and a resorcinol derivati
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(2013)
