Rhodium-catalyzed regioselective direct C-H arylation of indoles with aryl boronic acids

Article abstract of DOI:10.1016/j.tetlet.2015.04.015

A highly efficient Rh(III)-catalyzed direct C-H arylation of indoles with aryl boronic acids under mild conditions has been developed. The methodology features wide substrate scope and excellent functional group compatibility (34 examples, up to 99% yield). The arylated products can also be conveniently transformed into biologically active polycyclic indole derivatives.