Chemistry of Heterocyclic Compounds p. 449 - 453 (1992)
Update date:2022-08-03
Topics:
Deyanov, A. B.
Gavrilov, M. Yu.
Konshin, M. E.
Acetylation of 2-arylamino-5-carbethoxy-6-methylnicotinonitriles gave N-acetyl-2-arylamino-5-carbethoxy-6-methylnicotinonitriles, which, under the influence of hydrogen chloride, are cyclized to 1-aryl-1,4-dihydro-6-carbethoxy-2,7-dimethyl-4-oxopyrido<2,3-d>pyrimidines.The latter can be converted to the corresponding carboxylic and hydroxamic acids, as well as to acetylation products 1-aryl-2-acetonyl-1,4-dihydro-6-carbethoxy-7-methyl-4-oxopyrido<2,3-d>pyrimidines.
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Doi:10.1016/0022-328X(92)85029-V
(1992)Doi:10.1002/anie.201303134
(2013)Doi:10.1134/S1070428013060262
()Doi:10.1002/adsc.201701209
(2018)Doi:10.3762/bjoc.12.234
(2016)Doi:10.1016/S0040-4039(00)61160-7
(1992)
