
Analytical Chemistry p. 2352 - 2359 (1993)
Update date:2022-08-05
Topics:
Johnson, Arthur F.
Struthers, Mary D.
Pierson, Keith B.
Mangel, Walter F.
Smith, Lloyd M.
An alternative fluorescence-based method has been developed for the direct detection of small quantities of DNA in solution. In this system, a serine protease (elastase) is coupled to a DNA oligonucleotide through a disulfide linkage. A bis-(tetraalanine)
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Doi:10.1007/BF00767002
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(1985)