Stereochemistry of the Intramolecular Substitution of Phenylselenonyl Group by Nitrogen Atom in Amide. Inversion of Configuration

Article abstract of DOI:10.1246/cl.1992.2017

The stereochemistry of the intramolecular substitution of phenylselenonyl group by a nitrogen atom in tosylamino group was proved to be inversion by the oxidative cyclization of (S)-1-alkyl-4-(tosylamino)butyl phenyl selenides to (R)-N-tosyl-2-alkylpyrrolidines.