Cycloaromatization of α-oxoketene dithioacetals with enaminone derived carbanions

Article abstract of DOI:10.1016/S0040-4039(00)60035-7

Lithium enolates 3b and 6b derived from 1,3,6-trimethyluracil (3a) and 3-pyrrolidinocrotonate (6a) undergo regioselective γ-1,4- and γ-1,2-additions respectively with α-oxoketene dithioacetals 7 to yield the corresponding quinazolines and amino substituted aromatic compounds after subsequent cycloaromatization.