Chiral Organosilicon Compounds in Asymmetric Synthesis of Chiral 1,3-Diols

Article abstract of DOI:10.1021/jo00049a012

Chiral 1,3-diols can be prepared in high enantiomeric purity (>99percent ee) from the reactions of the chiral silylcarbanion 2 with epoxides followed by oxidative cleavage of the carbon-silicon bond with hydrogen peroxide.The absolute configurations of so