Mild and general palladium-catalyzed synthesis of methyl aryl ethers enabled by the use of a palladacycle precatalyst

DOI: 10.1021/ol401796v

Source and publish data:

Organic Letters p. 3998 - 4001 (2013)

Update date:2022-07-30

Topics:

Authors:

Cheung, Chi Wai

Buchwald, Stephen L.

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Article abstract of DOI:10.1021/ol401796v

A general method for the Pd-catalyzed coupling of methanol with (hetero)aryl halides is described. The reactions proceed under mild conditions with a wide range of aryl and heteroaryl halides to give methyl aryl ethers in high yield.

Full text of DOI:10.1021/ol401796v

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