Bulletin of the Chemical Society of Japan p. 2405 - 2412 (1988)
Update date:2022-08-04
Topics: Deprotection Dehydrogenation Purification Protection of Functional Groups
Matsumoto, Takashi
Imai, Sachihiko
Hayashi, Noriaki
In order to elucidate the absolute configuration of C-15 in natural 16-hydroxydehyroabietic acid, a metabolite of (+)-dehydroabietic acid in rabbits, methyl (+)-dehydroabietate was transformed into methyl (15S)-16-hydroxy-8,11,13-abietatrien-18-oate (3a) and its (15R)-epimer (3b).The synthetic 3a was identical with a methyl ester derived from the natural acid.Thus, the absolute configuration of C-15 in natural 16-hydroxydehydroabietic acid was conclusively assigned as an S-configuration.
View MoreSHANXI XINTIANYUAN PHARMACEUTICAL CO., LTD.
website:http://www.tychemical.com
Contact:0086-358-3521713 3521715
Address:No. 1 Yintong Road, Shanxi Jiaocheng Economic Development Zone, Xiajiaying Town, Jiaocheng County, Lvliang City, Shanxi Province, China
Qingdao XinYongAn Chemicals Co., Ltd
Contact:+86-532-81107967
Address:Chengyang dual-port industrial park by the sea，Qingdao
Zhejiang kehong chemical co., ltd
Contact:0086-575-85522000
Address:xiner center RD binhai industrial zone shaoxing zhejiang province P.R.China,312073
LinHai Cina Chemical Co., LTD.
Contact:0576-85580989
Address:Pharma-chem zone,Duqiao,Linhai,Zhejiang,China
Sinoway International (Jiangsu) Co., Ltd.
Contact:+86-25-86630167
Address:17 Beijing Road (West), Nanjing, China
Doi:10.1039/c3gc40946e
(2013)Doi:10.1039/c3cc43188f
(2013)Doi:10.1016/j.bmcl.2013.07.016
(2013)Doi:10.1021/ja408114u
(2013)Doi:10.1021/jo4010603
(2013)Doi:10.1080/00397919208021114
(1992)
