Bulletin of the Chemical Society of Japan p. 2405 - 2412 (1988)
Update date:2022-08-04
Topics: Deprotection Dehydrogenation Purification Protection of Functional Groups
Matsumoto, Takashi
Imai, Sachihiko
Hayashi, Noriaki
In order to elucidate the absolute configuration of C-15 in natural 16-hydroxydehyroabietic acid, a metabolite of (+)-dehydroabietic acid in rabbits, methyl (+)-dehydroabietate was transformed into methyl (15S)-16-hydroxy-8,11,13-abietatrien-18-oate (3a) and its (15R)-epimer (3b).The synthetic 3a was identical with a methyl ester derived from the natural acid.Thus, the absolute configuration of C-15 in natural 16-hydroxydehydroabietic acid was conclusively assigned as an S-configuration.
View MoreFREEBARQUE DEVELOPMENT GROUP LIMITED
Contact:+86(0)10-5109 5335 or 5109 5345
Address:Room602,Block1-B,LINGDI OFFICE,NO.13 BEIYUAN ROAD
Hunan Zhongqi Pharmaceutical Co., Ltd
website:http://www.hnzqzy.com
Contact:0730-8722288 13807308622
Address:Wanjiafan Road ,Yueyang Economic And Technological Development Zone ,Hunan,PRC
Rizhao Lanxing Chemical Indusrial Co.,Ltd
Contact:86-633-2616708
Address:NO.15 West road Shenglan, Lanshan district, Rizhao City
Changsha Huajing Powdery Material Technological Co., Ltd.
Contact:86-731-88879686
Address:Building 2, West Garden, Main Campus of Central South University, Changsha, Hunan Province, China
Shuanghe Bio-Technology Limited(expird)
Contact:+86-571-61710758,18968016640
Address:Jinqiao north road 916# Fuyang
Doi:10.1039/c3gc40946e
(2013)Doi:10.1039/c3cc43188f
(2013)Doi:10.1016/j.bmcl.2013.07.016
(2013)Doi:10.1021/ja408114u
(2013)Doi:10.1021/jo4010603
(2013)Doi:10.1080/00397919208021114
(1992)
