Synthesis of biologically active [2.2]paracyclophanes

DOI: 10.1002/ardp.19923251002

Source and publish data:

Archiv der Pharmazie p. 625 - 628 (1992)

Update date:2022-09-26

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Authors:

Aly Aly

Hassan Hassan

Mourad Mourad

Hopf Hopf

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Article abstract of DOI:10.1002/ardp.19923251002

Claisen reaction of 4-acetyl[2.2]paracyclophane (1) with ethyl acetate and diethyl oxalate affords 4-acetoacetyl[2.2]paracyclophane (2) and ethyl(4-oxaloacetyl[2.2]paracyclophane) (6), respectively. Reaction of 2 and 6 with hydrazines and CuCl₂

Full text of DOI:10.1002/ardp.19923251002

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Product name:1-benzyl-3(<2.2>paracyclophanoyl)piperidin-4-one

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