Direct α-hydroxylation of ketones under acidic conditions using [bis(trifluoroacetoxy)]iodobenzene

DOI: 10.1016/S0040-4039(00)60007-2

Source and publish data:

Tetrahedron Letters p. 6065 - 6068 (1992)

Update date:2022-07-29

Topics:

Authors:

Moriarty

Berglund

Penmasta

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Article abstract of DOI:10.1016/S0040-4039(00)60007-2

[Bis(trifluoroacetoxy)] iodobenzene and trifluoroacetic acid in CH₃CN/H₂O reacts with aromatic, heteroaromatic, and aliphatic ketones to afford α-hydroxyketones in moderate to good yields.

Full text of DOI:10.1016/S0040-4039(00)60007-2

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