Direct α-hydroxylation of ketones under acidic conditions using [bis(trifluoroacetoxy)]iodobenzene

DOI: 10.1016/S0040-4039(00)60007-2

Source and publish data:

Tetrahedron Letters p. 6065 - 6068 (1992)

Update date:2022-07-29

Topics:

Authors:

Moriarty

Berglund

Penmasta

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)60007-2

[Bis(trifluoroacetoxy)] iodobenzene and trifluoroacetic acid in CH₃CN/H₂O reacts with aromatic, heteroaromatic, and aliphatic ketones to afford α-hydroxyketones in moderate to good yields.

Full text of DOI:10.1016/S0040-4039(00)60007-2

Products guided by the article

Product name:1-(2,5-Dimethyl-thiophen-3-yl)-2-hydroxy-ethanone

Cas No:145070-50-4

R&D Labs maybe for 145070-50-4

RongCheng K&S Chemical Co.,Ltd

Contact:0631-7336369

Address:rongcheng ,shandong province china
Weinan Rigel Pharm Co., Ltd.

Contact:+86-913-2223392

Address:No. 32, Xinanjing Road, Weinan City, Shaanxi Province, 714000, China
Melone Pharmaceutical Co., ltd

Contact:+86-411 82593920, 82593631

Address:No 232, JInma Roda, Development Zone, Dalian, China
NEWSTAR CHEM ENTERPRISE LTD.

Contact:0572-2722882

Address:1201,F3,xinghuibandao,
Nanjing Zelang Medical Technology Co. Ltd

Contact:86-25-83063290/13770714480

Address:Ganjiabian 108# 01 Unit,701-702 room,Yao Hua Street,Qixia District,Nanjing,Jiangsu,China

Relevant to this article

Regioselective diversification of a cardiac glycoside, lanatoside C, by organocatalysis

Doi:10.1021/jo301007x
(2012)
Unexpected base-promoted synthesis of tetrasubstituted furans via palladium-catalyzed oxidation and cyclization of carbon-carbon triple bond with molecular oxygen

Doi:10.1055/s-0031-1290526
(2012)
Reactive metabolite trapping studies on imidazo- and 2-methylimidazo[2,1-b] thiazole-based inverse agonists of the ghrelin receptor s

Doi:10.1124/dmd.113.051839
(2013)
Synthesis and fluorescence properties of thiazole-boron complexes bearing a β-ketoiminate ligand

Doi:10.1021/ol302179r
(2012)
Cytotoxicity and anti-HIV evaluations of some new synthesized quinazoline and thioxopyrimidine derivatives using 4-(thiophen-2-yl)-3,4,5,6- tetrahydrobenzo[h]quinazoline-2(1H)-thione as synthon

Doi:10.1007/s12039-012-0242-4
(2012)
Bismuth(iii)-catalyzed cycloisomerization and (hetero)arylation of alkynols: Simple access to 2-(hetero)aryl tetrahydrofurans and tetrahydropyrans

Doi:10.1039/c8ob00368h
(2018)

Article Doi