Direct α-hydroxylation of ketones under acidic conditions using [bis(trifluoroacetoxy)]iodobenzene

DOI: 10.1016/S0040-4039(00)60007-2

Source and publish data:

Tetrahedron Letters p. 6065 - 6068 (1992)

Update date:2022-07-29

Topics:

Authors:

Moriarty

Berglund

Penmasta

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)60007-2

[Bis(trifluoroacetoxy)] iodobenzene and trifluoroacetic acid in CH₃CN/H₂O reacts with aromatic, heteroaromatic, and aliphatic ketones to afford α-hydroxyketones in moderate to good yields.

Full text of DOI:10.1016/S0040-4039(00)60007-2

Products guided by the article

Product name:1-(2,5-Dimethyl-thiophen-3-yl)-2-hydroxy-ethanone

Cas No:145070-50-4

R&D Labs maybe for 145070-50-4

Beijing Mediking Biopharm Co., Ltd.

Contact:+86-10-89753524/81760121/81769521

Address:Hongxianghong Incubator, Beiqijia Town, Changping district, Beijing, China
Shanghai Xinda Pharmaceuticals Co., Ltd.

Contact:86-21-33692333-8008

Address:999 Linxian Road, Jinshan Industrial Park, Shanghai, China
LinHai Cina Chemical Co., LTD.

Contact:0576-85580989

Address:Pharma-chem zone,Duqiao,Linhai,Zhejiang,China
Mashilabs(shanghai)Co.,ltd

Contact:+86-21-54391580

Address:Room 502,No.65,Lane 2388 Hongxin Road,Shanghai,China
Ji'an Kexin Trade Co., Ltd.(expird)

Contact:86-0796-8187704 18507063190

Address:ji'an jiangxi

Relevant to this article

Regioselective diversification of a cardiac glycoside, lanatoside C, by organocatalysis

Doi:10.1021/jo301007x
(2012)
Unexpected base-promoted synthesis of tetrasubstituted furans via palladium-catalyzed oxidation and cyclization of carbon-carbon triple bond with molecular oxygen

Doi:10.1055/s-0031-1290526
(2012)
Reactive metabolite trapping studies on imidazo- and 2-methylimidazo[2,1-b] thiazole-based inverse agonists of the ghrelin receptor s

Doi:10.1124/dmd.113.051839
(2013)
Synthesis and fluorescence properties of thiazole-boron complexes bearing a β-ketoiminate ligand

Doi:10.1021/ol302179r
(2012)
Cytotoxicity and anti-HIV evaluations of some new synthesized quinazoline and thioxopyrimidine derivatives using 4-(thiophen-2-yl)-3,4,5,6- tetrahydrobenzo[h]quinazoline-2(1H)-thione as synthon

Doi:10.1007/s12039-012-0242-4
(2012)
Bismuth(iii)-catalyzed cycloisomerization and (hetero)arylation of alkynols: Simple access to 2-(hetero)aryl tetrahydrofurans and tetrahydropyrans

Doi:10.1039/c8ob00368h
(2018)

Article Doi