New α,β-Didehydroamino Acid Derivatives as Precursors in the Synthesis of 1-Aminocyclopropanecarboxylic Acids

Article abstract of DOI:10.1016/S0040-4020(01)85381-3

The reaction of N-(diphenylmethylene)didehydroalanine methyl ester and N-didehydroalanine methyl ester with diazoalkanes or ylides gives the corresponding cyclopropane derivatives in high yields.The cis/trans ratio of these compounds was dependent on substrate, reagent and reaction temperature.From stereochemically homogeneous compounds the corresponding 1-aminocyclopropanecarboxylic acids were easily obtained by acid hydrolysis.