A Cycloadditive Route to Trifluoromethyl-substituted Aminoalcohols

DOI: 10.1016/S0040-4020(01)81194-7

Source and publish data:

Tetrahedron p. 9775 - 9788 (1992)

Update date:2022-07-30

Topics:

Authors:

Bravo, Pierfrancesco

Bruche, Luca

Fronza, Giovanni

Zecchi, Gaetano

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Article abstract of DOI:10.1016/S0040-4020(01)81194-7

A synthetic approach to the title compounds is described, involving the 1,3-dipolar cycloaddition of nitrones to trifluoromethyl-substituted alkene derivatives, followed by reductive ring opening of the so obtained isoxazolidines.

Full text of DOI:10.1016/S0040-4020(01)81194-7

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