Tricyclic 'oxadiazoaphosphorine oxide' guanosines: A new strategy to the protection of guanine bases during RNA synthesis

DOI: 10.1016/S0040-4039(00)61764-1

Source and publish data:

Tetrahedron Letters p. 6739 - 6742 (1992)

Update date:2022-08-04

Topics:

Authors:

Damha Damha

Guo Guo

Zabarylo

Ganeshan

Giannaris

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Article abstract of DOI:10.1016/S0040-4039(00)61764-1

A novel strategy for simultaneously protecting the lactam and N2-amino functions of guanine nucleosides is reported. N2-benzoylated guanosines were readily converted into tricyclic 'oxadiazophosphorine oxide' guanosines upon reaction with N,N-diisopropylp

Full text of DOI:10.1016/S0040-4039(00)61764-1

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