New Type of Cyclization of α,β,χ,ψ-Unsaturated Dioic Acid Esters through Tandem Conjugate Additions by Using Lithium N-Benzyl-N-(trimethylsilyl)amide as a Nitrogen Nucleophile

DOI: 10.1021/jo00037a034

Source and publish data:

Journal of Organic Chemistry p. 3139 - 3145 (1992)

Update date:2022-08-04

Topics: Cyclization

Authors:

Uyehara, Tadao

Shida, Naomi

Yamamoto, Yoshinori

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00037a034

Treatment of dimethyl (2E,6E)-2,6-octadienedioate with lithium N-benzyl-N-(trimethylsilyl)amide (LSA) gave 5-exo-trig ring closure products, methyl 3-(N-benzylamino)-2-(methoxycarbonyl)cyclopentane-1-acetates, through tandem conjugate additions.The relate

Full text of DOI:10.1021/jo00037a034

Products guided by the article

Product name:Ethyl trans-2-(N-Benzylamino)cyclohexanecarboxylate

Cas No:145822-62-4

R&D Labs maybe for 145822-62-4

Puyang Willing Chemicals Co.,Ltd.

Contact:86-393-4840366

Address:Puyang Henan China
Jintan Jinnuo Chemical Co., Ltd.

Contact:+86-519-80199901

Address:Room 1804, Building 1, Huacheng Business Plaza, Jintan, Jiangsu, China
Mashilabs(shanghai)Co.,ltd

Contact:+86-21-54391580

Address:Room 502,No.65,Lane 2388 Hongxin Road,Shanghai,China
Chemtrade International ( China )

Contact:+86-532-86893005

Address:Rm 2-501, Huaxia Zonghe Building, No. 410 JInggangshan Road, Huangdao
jiangsu haian chemical co.,ltd.

Contact:86-513-15851283853

Address:No.99,Changjiang West Road,Haian County,Jiangsu Province,China

Relevant to this article

Carbene-9-BBN ring expansions as a route to intramolecular frustrated lewis pairs for CO₂ reduction

Doi:10.1002/chem.201304870
(2014)
Synthesis of new metallomesogens based on 3-ketoesters

Doi:10.1134/S1070363213080148
(2013)
Caffeine gold complex supported on magnetic nanoparticles as a green and high turnover frequency catalyst for room temperature A³ coupling reaction in water

Doi:10.1002/aoc.4760
(2019)
Synthesis, antitubercular and anticancer activity of new Baylis-Hillman adduct-derived N-cinnamyl-substituted isatin derivatives

Doi:10.1007/s00044-013-0787-x
(2014)
Selective synthesis of optically active 3-haloazetidin-2-ones or aziridines by the condensation of various metal enolates of α-haloacetate with a chiral imine

Doi:10.1016/S0040-4039(00)74774-5
(1992)
Synthesis of enantiomerically pure β- and γ-amino acids from aspartic and glutamic acid derivatives

Doi:10.1055/s-1992-26315
(1992)

Article Doi