Substituted 3-(Phenylmethyl)-1H-indole-5-carboxamides and 1-(Phenylmethyl)indole-6-carboxamides as Potent, Selective, Orally Active Antagonists of the Peptidoleukotrienes

DOI: 10.1021/jm00055a011

Source and publish data:

Journal of Medicinal Chemistry p. 394 - 409 (1993)

Update date:2022-08-02

Topics:

Authors:

Jacobs, Robert T.

Brown, Frederick J.

Cronk, Laura A.

Aharony, David

Buckner, Carl K.

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00055a011

Substituted indole-5-caboxamides and indole-6-carboxamides have been found to be potent and selective antagonists of the peptidoleukotrienes.Initial derivatives of these series (4-<<5-<(cyclopentylmethyl)carbamoyl>-1-methylindol-3-yl>methyl>-3-methoxy-N-<

Full text of DOI:10.1021/jm00055a011

Products guided by the article

Product name:methyl 4-<<6-<(2-ethylbutyl)carbamoyl>indol-1-yl>methyl>-3-methoxybenzoate

Cas No:145889-33-4

R&D Labs maybe for 145889-33-4

Yingkou Sanzheng Organic Chemical Co. Ltd.

Contact:+86-417-3638818

Address:25 Gengxinli Village, Daqing Road, Yingkou, Liaoning, China
Refine Chemicals Science & Technology Technology Developing Co., Ltd.

Contact:+86-22-87899130

Address:No.12,west keyan road,Tianjin City
Tengzhou Runlong Fragrance Co., Ltd.

website:http://www.tzrunlong.com/

Contact:0086-15665710862

Address:No. 78, Fushan Road, Biomedical Industrial Park, Dawu Town, Tengzhou, Shandong, 277514 China
Shanghai Yuking Water Soluble Material Tech Co., Ltd

Contact:86-21-68286299

Address:4F, 13B, No. 600, South Xinyuan Road 201306, Shanghai, China
Jinan Hongfangde Pharmatech Co.,Ltd

Contact:86-531-88870908

Address:F Bldg. West Unit North Area of Univ. Tech. Garden Xinyu Rd. Jinan New & High Tech Industry Development Zone Shandong, China

Relevant to this article

Preparation of enantiomerically pure sulfoxides from lactic acid and 3-hydroxybutyric acid. Isopropenyl tolyl sulfoxide and 2-(phenylsulfinyl)acrylate

Doi:10.1055/s-1992-26328
(1992)
Doi:10.1016/0040-4020(67)80088-7
(1967)
A NEW SYNTHETIC ROUTE TO TROPANE ALKALOIDS. PSEUDOTROPINE AND TROPACOCAINE

Doi:10.1016/S0040-4039(01)91127-X
(1984)
Discovery and Early Clinical Development of LY3202626, a Low-Dose, CNS-Penetrant BACE Inhibitor

Doi:10.1021/acs.jmedchem.1c00489
(2021)
Photo-biocatalytic One-Pot Cascades for the Enantioselective Synthesis of 1,3-Mercaptoalkanol Volatile Sulfur Compounds

Doi:10.1002/anie.201802135
(2018)
Base-promoted oxygenation of N-substituted-N-tosylhydrazines - A convenient route to hydroxydeamination of primary amines

Doi:10.1016/S0040-4039(00)60796-7
(1992)

Article Doi