Substituted 3-(Phenylmethyl)-1H-indole-5-carboxamides and 1-(Phenylmethyl)indole-6-carboxamides as Potent, Selective, Orally Active Antagonists of the Peptidoleukotrienes

DOI: 10.1021/jm00055a011

Source and publish data:

Journal of Medicinal Chemistry p. 394 - 409 (1993)

Update date:2022-08-02

Topics:

Authors:

Jacobs, Robert T.

Brown, Frederick J.

Cronk, Laura A.

Aharony, David

Buckner, Carl K.

et al. et al.

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Article abstract of DOI:10.1021/jm00055a011

Substituted indole-5-caboxamides and indole-6-carboxamides have been found to be potent and selective antagonists of the peptidoleukotrienes.Initial derivatives of these series (4-<<5-<(cyclopentylmethyl)carbamoyl>-1-methylindol-3-yl>methyl>-3-methoxy-N-<

Full text of DOI:10.1021/jm00055a011

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