Preparation of enantiomerically pure sulfoxides from lactic acid and 3-hydroxybutyric acid. Isopropenyl tolyl sulfoxide and 2-(phenylsulfinyl)acrylate

Article abstract of DOI:10.1055/s-1992-26328

The EPC-synthesis of sulfoxides from readily available starting materials ('chiral pool') is demonstrated for the first time. Cyclic and open-chain thioethers derived from lactic and 3-hydroxybutyric acid are oxidized to sulfoxides, and the resulting prod