
Journal of medicinal chemistry p. 617 - 626 (1993)
Update date:2022-08-05
Topics:
Hayashi
Miwa
Ichikawa
Yoda
Miki
Ishii
Kono
Yasuzawa
Suzuki
A series of 4-hydroxy-3-quinolinecarboxylic acid derivatives (6) and 4-hydroxy-2-oxo-1,2-dihydro-3-quinolinecarboxylic acid derivatives (7) were designed and synthesized as 5-HT3 receptor antagonists. Molecular modeling studies suggested that the 3-carbon
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