5-HT3 receptor antagonists. 2. 4-Hydroxy-3-quinolinecarboxylic acid derivatives.

DOI: 10.1021/jm00057a011

Source and publish data:

Journal of medicinal chemistry p. 617 - 626 (1993)

Update date:2022-08-05

Topics:

Authors:

Hayashi Hayashi

Miwa Miwa

Ichikawa

Yoda Yoda

Miki Miki

Ishii Ishii

Kono Kono

Yasuzawa

Suzuki Suzuki

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Article abstract of DOI:10.1021/jm00057a011

A series of 4-hydroxy-3-quinolinecarboxylic acid derivatives (6) and 4-hydroxy-2-oxo-1,2-dihydro-3-quinolinecarboxylic acid derivatives (7) were designed and synthesized as 5-HT3 receptor antagonists. Molecular modeling studies suggested that the 3-carbon

Full text of DOI:10.1021/jm00057a011

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