Probing the radical mechanism of galactose oxidase using an ultrafast radical probe

Article abstract of DOI:10.1016/S0960-894X(99)00611-3

Processing of trans-2-phenylcyclopropylmethanols 5 and 6 by the monocopper/tyrosine radical enzyme galactose oxidase led to mechanism-based inactivation with a partition ratio, (k(cat) + k(inact))/k(inact), of approximately 1 and a primary deuterium isoto