Chemical and Pharmaceutical Bulletin p. 2399 - 2409 (1992)
Update date:2022-08-04
Topics:
Tsuji
Nakamura
Konishi
Okumura
Matsuo
Various 2'-phenoxymethanesulfonanilide derivatives were synthesized and evaluated for antiinfiammatory and analgesic activities. Some compounds bearing an electron-attracting substituent at the 4'-position strongly inhibited adjuvant-induced arthritis in rats and acetic acid-induced writhing syndrome in mice without causing gastro-intestinal irritation. Among them, 4'-cyano-(FK867) and 4'-acetyl-(FK3311) 2'-(2,4-difluorophenoxy)methanesulfonanilides were selected as the candidates for further development.
View MoreZhejiang Rongkai Chemical Technology Co.,Ltd.
Contact:+86-578-8185786
Address:Shangjiang Industrial Zone,Suichang
HangZhou HuaYe Chemical Technology Co.,Ltd
Contact:+86-13505815007
Address:hangzhou
Contact:+86-533-3112891
Address:zibo
Longhui qunfeng Chemical Co., Ltd
Contact:86-731-82173407
Address:South-east Industrial Park, Longhui County, Hunan Province, China
Shanghai Sunwise Chemical Co., Ltd
website:http://www.sunwisechem.com
Contact:86-021-33883180
Address:Room 10E, Building G, Westlink Center, No. 2337 Gudai Road, Minhang District, Shanghai, China PC: 201100
Doi:10.1016/S0040-4039(00)60821-3
(1992)Doi:10.1016/S0040-4039(00)61009-2
(1992)Doi:10.1016/S0022-328X(98)00482-3
(1998)Doi:10.1016/0040-4039(93)85051-W
(1993)Doi:10.1016/j.carres.2013.07.008
(2013)Doi:10.1002/anie.201607752
(2016)
