Conversion of N-acyl-2,3-dihydro-4-pyridones to 4-chloro-1,2-dihydropyridines using the Vilsmeier reagent

DOI: 10.1016/0040-4039(93)88003-2

Source and publish data:

Tetrahedron Letters p. 7635 - 7638 (1992)

Update date:2022-08-04

Topics:

Authors:

Al-Awar Al-Awar

Joseph Joseph

Comins Comins

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0040-4039(93)88003-2

N-Acyl-2,3-dihydro-4-pyridones are converted to 1-acyl-4-chloro-1,2-dihydropyridines in one step using one equivalent of Vilsmeier reagent. This conversion was utilized in an asymmetric synthesis of (-)-coniine.

Full text of DOI:10.1016/0040-4039(93)88003-2

Products guided by the article

Product name:(2S,6R)-4-Chloro-5-formyl-2,6-dipropyl-3,6-dihydro-2H-pyridine-1-carboxylic acid benzyl ester

Cas No:146254-02-6

R&D Labs maybe for 146254-02-6

Sichuan Highlight Fine Chemicals Co., Ltd.

Contact:+86-28-8525 1605

Address:A5-102 Airport base,388 West Airport Huang He Zhong Lu,2 Section
Shandong Wanda Organosilicon New Material Co., Ltd

Contact:+86-21-54177116;54302881

Address:R1318 Greenland No. 3 Lane 58 Xinjian East Rd., Minhang
Nanjing Samwon International Limited

Contact:+86-25-84873444

Address:1108, BLDG B, New Century Plaza, No 1, South Taiping Rd.,
HOST COUNTRY LIMITED

Contact:+852 83038667

Address:Room 1502, 15th Floor, SPA Centre,53-55 Lockhart Road, Wanchai, Hong Kong
Du-Hope International Group

website:http://www.np-chem.com

Contact:0086-25-52346877

Address:199, Jian Ye Road, Nanjing, China

Relevant to this article

Reactions of aqueous copper acetate with triethylamine and 3,5-dimethylpyrazole

Doi:10.1134/S0036023610050104
(2010)
An integrated approach to the synthesis of continguously substituted xanthopurpurins, pachybasins and purpurins

Doi:10.1016/S0040-4020(01)80322-7
(1993)
Efficient synthesis of 2-amino-6-arylbenzothiazoles via Pd(0) Suzuki cross coupling reactions: Potent urease enzyme inhibition and nitric oxide scavenging activities of the products

Doi:10.3390/molecules18088845
(2013)
Enantioselective synthesis of chiral liquid crystalline compounds from monoterpenes

Doi:10.1016/S0040-4020(01)86265-7
(1993)
Synthesis of the C-5 homologue of N-acetylneuraminic acid by enzymatic chain elongation of 2-C-acetamidomethyl-2-deoxy-D-mannose

Doi:10.1016/S0040-4039(00)74709-5
(1992)
Design, synthesis and biological evaluation of novel naphthoquinone derivatives as IDO1 inhibitors

Doi:10.1016/j.ejmech.2018.08.013
(2018)

Article Doi