Conversion of N-acyl-2,3-dihydro-4-pyridones to 4-chloro-1,2-dihydropyridines using the Vilsmeier reagent

DOI: 10.1016/0040-4039(93)88003-2

Source and publish data:

Tetrahedron Letters p. 7635 - 7638 (1992)

Update date:2022-08-04

Topics:

Authors:

Al-Awar Al-Awar

Joseph Joseph

Comins Comins

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0040-4039(93)88003-2

N-Acyl-2,3-dihydro-4-pyridones are converted to 1-acyl-4-chloro-1,2-dihydropyridines in one step using one equivalent of Vilsmeier reagent. This conversion was utilized in an asymmetric synthesis of (-)-coniine.

Full text of DOI:10.1016/0040-4039(93)88003-2

Products guided by the article

Product name:(2S,6R)-4-Chloro-5-formyl-2,6-dipropyl-3,6-dihydro-2H-pyridine-1-carboxylic acid benzyl ester

Cas No:146254-02-6

R&D Labs maybe for 146254-02-6

Huangshan Honghui Pharm Technology Co., Ltd.(expird)

website:http://www.honghuichem.com

Contact:18855958372

Address:Qingshan Wan No.1,Nanyuan Kou,SheXian Huangshan City,Anhui Province
WUHU HUAHAI BIOLOGY ENGINEERING CO LTD

Contact:+86-553-3836920

Address:7/F NO.82 LAODONG ROAD WUHU CHINA
Nantong Kaixin Pharma Chemical Co.,Ltd.

Contact:86-513-85250786

Address:2-1103 Huachen Mansion, 111 Gongnong Road,Nantong, Jiangsu, China
Shuanghe Bio-Technology Limited(expird)

Contact:+86-571-61710758,18968016640

Address:Jinqiao north road 916# Fuyang
Tocopharm Co., Ltd.

Contact:+86-021-6989-5597

Address:No.80 Yichuan Rd., Putuo District,Shanghai,P.R.China

Relevant to this article

Reactions of aqueous copper acetate with triethylamine and 3,5-dimethylpyrazole

Doi:10.1134/S0036023610050104
(2010)
An integrated approach to the synthesis of continguously substituted xanthopurpurins, pachybasins and purpurins

Doi:10.1016/S0040-4020(01)80322-7
(1993)
Efficient synthesis of 2-amino-6-arylbenzothiazoles via Pd(0) Suzuki cross coupling reactions: Potent urease enzyme inhibition and nitric oxide scavenging activities of the products

Doi:10.3390/molecules18088845
(2013)
Enantioselective synthesis of chiral liquid crystalline compounds from monoterpenes

Doi:10.1016/S0040-4020(01)86265-7
(1993)
Synthesis of the C-5 homologue of N-acetylneuraminic acid by enzymatic chain elongation of 2-C-acetamidomethyl-2-deoxy-D-mannose

Doi:10.1016/S0040-4039(00)74709-5
(1992)
Design, synthesis and biological evaluation of novel naphthoquinone derivatives as IDO1 inhibitors

Doi:10.1016/j.ejmech.2018.08.013
(2018)

Article Doi