The synthesis of 1,6-disubstituted indanes which mimic the orientation of amino acid side-chains in a protein alpha-helix motif.

DOI: 10.1016/S0040-4039(00)61800-2

Source and publish data:

Tetrahedron Letters p. 6879 - 6882 (1992)

Update date:2022-08-03

Topics:

Authors:

Nolan Nolan

Ratcliffe

Rees Rees

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Article abstract of DOI:10.1016/S0040-4039(00)61800-2

We utilize a 1,6-disubstituted indane as a template onto which two amino acid side-chains are appended in an orientation which mimics that found in a protein alpha-helix motif.

Full text of DOI:10.1016/S0040-4039(00)61800-2

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