Use of the N-formyliminium ion cyclization for the synthesis of 3-aryl-1,2,3,4-tetrahydroisoquinolines

Article abstract of DOI:10.1055/s-1992-26350

Classical cyclization procedures for the synthesis of 3-arylisoquinolines are fraught with complications. Here, we present the application of an N-acyliminium cyclization to such target molecules. N(1,2-diarylethyl)formamides 1, 4a-4d, and 4f were cyclize