A convenient synthesis of N-protected diphenyl phosphonate ester analogues of ornithine, lysine and homolysine

DOI: 10.1016/S0040-4039(00)73578-7

Source and publish data:

Tetrahedron Letters p. 2847 - 2850 (1993)

Update date:2022-08-03

Topics:

Authors:

Hamilton

Walker Walker

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Article abstract of DOI:10.1016/S0040-4039(00)73578-7

A 3-step synthesis to the title compounds has been developed which provides them differentially protected at nitrogen. These could then be selectively deprotected using hydrazine hydrate or hydrogenolysis over Pd/C.

Full text of DOI:10.1016/S0040-4039(00)73578-7

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Product name:[1-Amino-4-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-butyl]-phosphonic acid diphenyl ester

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