Tetrahedron Letters p. 4917 - 4920 (1987)
Update date:2022-09-26
Topics:
Corey, E. J.
Nagata, Ryu
Wright, Stephen W.
A biomimetic synthesis of colneleic acid (2) from 9(S)-hydroperoxy-10(E),12(Z)octadecadienoic acid (1) is reported.The lipoxygenase of potato which converts linoleic acid to 1 was found to be strongly inhibited by acid 2 (Ki=8μM).
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