REACTIONS OF 5,6-DIAMINO-1,3-DIMETYLURACIL WITH HALOGEN DERIVATIVES OF CHALCONES

Article abstract of DOI:10.1007/BF00474494

The reaction of 5,6-diamino-1,3-dimethyluracil with 1,3-diaryl-2,3-dibromopropan-1-ones gave β-(5-amino-6-imino-1,3-dimethyluracil)chalcones, and conditions for their cyclocondensation to pyrimidinodiazepines were found.For substantiation of the reaction mechanism, the reaction of the diamine with other halogen derivatives of chalcones was studied.The IR, UV, and mass spectra of the synthesized compounds and their condensation products are discussed.