cis-1,2,3a,4,5,9b-Hexahydro-3H-benz[e]indoles: Synthesis and in vitro binding affinity at dopamine D1 and D2 receptors

Article abstract of DOI:10.1002/jps.2600820324

cis-1,2,3a,4,5,9b-Hexahydro-3H-benz[e]indoles were synthesized and evaluated for in vitro dopamine D1 and D2 receptor binding affinity. The target compounds 21-25 were readily prepared by reduction of the air- sensitive tricyclic enamines 10-14. Reduction