Diastereoselective synthesis and optical resolution of 3,4-substituted tetrahydroisoquinolin-4-ols

DOI: 10.1016/S0040-4020(01)86282-7

Source and publish data:

Tetrahedron p. 1017 - 1024 (1993)

Update date:2022-08-03

Topics:

Authors:

Kihara, Masaru

Ikeuchi, Motoki

Jinno, Kaori

Kashimoto, Minoru

Kobayashi, Yoshimaro

Nagao, Yoshimitsu

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4020(01)86282-7

Trans-3,4-substituted 1,2,3,4-tetrahydroisoquinolin-4-ols were prepared diastereoselectively by an insertion reaction with zerovalent nickel and by Barbier reaction with butyllithium of N-(2-iodobenzyl)phenacylamines. The isoquinolin-4-ols were resolved by means of HPLC method and the absolute configurations were determined.

Full text of DOI:10.1016/S0040-4020(01)86282-7

Products guided by the article

Product name:α-ethyl-N-(2-iodobenzyl)-N-methylphenacylamine

Cas No:147749-70-0

R&D Labs maybe for 147749-70-0

Suzhou HeChuang Chemical Co.,Ltd.

Contact:+86-512-88800520

Address:No.9 Guanchao Rd,Changshu Advanced Materials Industy Park
Longhui qunfeng Chemical Co., Ltd

Contact:86-731-82173407

Address:South-east Industrial Park, Longhui County, Hunan Province, China
Xian Lyphar Biotech Co., Ltd.

Contact:0086-29-89196322

Address:North of the Fifth Keji Road, Hi-Tech Industrial Zone, Xi'an City, Shaanxi Province, China
ANGCHEN BRIGHTCHEM CO., LTD

website:http://www.angchenchem.com

Contact:+86-510-88302099 82327577

Address:Rm. 404/405, Floor 4th, No. 983 FengXiang Road, Wuxi, China
Xi'an Kaixiang Photoelectric Technology Co., Ltd

website:http://www.kxmaterials.com/

Contact:86-29-15991651477

Address:Building 6, Biopharmaceutical Industry R&D Cluster Base, No. 16, Caotang 4th Road, Caotang Science and Technology Industrial Base, High-tech Zone, Xi'an City, Shaanxi Province, China

Relevant to this article

N⁷-DNA: Synthesis and base pairing of oligonucleotides containing 7-(2-deoxy-β-D-erythro-pentofuranosyl)adenine (N⁷A(d))

Doi:10.1002/hlca.19940770302
(1994)
The role of torsional isomers of planarly chiral nonbridged bis(indenyl)metal type complexes in stereoselective propene polymerization

Doi:10.1021/ja00064a022
(1993)
Dibenzoxepin derivatives: Thromboxane A₂ synthase inhibition and thromboxane A₂ receptor antagonism combined in one molecule

Doi:10.1021/jm00063a011
(1993)
Cooperative ruthenium complex catalyzed multicomponent synthesis of pyrimidines

Doi:10.1039/c9dt04040d
(2019)
REGIOSELECTIVE PALLADIUM(0) CATALYZED REDUCTION OF 1-ALKENYLCYCLOPROPYL ESTERS AS EQUIVALENT TO THE WITTIG REACTION

Doi:10.1016/S0040-4039(00)92074-4
(1992)
Stereocontrolled Synthesis of R or S, E or Z Unsaturated α-Amino Acids by Enantio- and Diastereoselective Epoxidation of δ-Hydroxy Allylic Phosphine Oxides

Doi:10.1016/S0040-4039(00)91787-8
(1993)

Article Doi