Diastereoselective synthesis and optical resolution of 3,4-substituted tetrahydroisoquinolin-4-ols

DOI: 10.1016/S0040-4020(01)86282-7

Source and publish data:

Tetrahedron p. 1017 - 1024 (1993)

Update date:2022-08-03

Topics:

Authors:

Kihara, Masaru

Ikeuchi, Motoki

Jinno, Kaori

Kashimoto, Minoru

Kobayashi, Yoshimaro

Nagao, Yoshimitsu

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4020(01)86282-7

Trans-3,4-substituted 1,2,3,4-tetrahydroisoquinolin-4-ols were prepared diastereoselectively by an insertion reaction with zerovalent nickel and by Barbier reaction with butyllithium of N-(2-iodobenzyl)phenacylamines. The isoquinolin-4-ols were resolved by means of HPLC method and the absolute configurations were determined.

Full text of DOI:10.1016/S0040-4020(01)86282-7

Products guided by the article

Product name:α-ethyl-N-(2-iodobenzyl)-N-methylphenacylamine

Cas No:147749-70-0

R&D Labs maybe for 147749-70-0

Yurui(Shanghai)Chemical Co.,Ltd

Contact:0086 21-50456736

Address:No.3188 Xiupu Road,Shanghai
Xi'an Herbland Tech Inc.

Contact:+86-29-88710656

Address:South Tai bai Road, High Tech Development Zone, Xi'an China
GUANGZHOU MEDCAN PHARMATECH LTD

website:http://www.gzmedcan.com

Contact:+86-20-82519649

Address:Building J,Room 101,1 JiangtashanRd,Guang Zhou Science City,Guang Zhou ,China
Chengdu D-Innovation Pharmaceutical Co., Ltd

Contact:86-28-85105536

Address:1001, B6, No.88 Keyuan South Road, Chengdu Hi-Tech Zone
Suzhou Tianma Specialty Chemicals Co.,Ltd

Contact:+86-512-68090577

Address:#199, Huayuan Rd, Mudu, Suzhou, Jiangsu, CHINA

Relevant to this article

N⁷-DNA: Synthesis and base pairing of oligonucleotides containing 7-(2-deoxy-β-D-erythro-pentofuranosyl)adenine (N⁷A(d))

Doi:10.1002/hlca.19940770302
(1994)
The role of torsional isomers of planarly chiral nonbridged bis(indenyl)metal type complexes in stereoselective propene polymerization

Doi:10.1021/ja00064a022
(1993)
Dibenzoxepin derivatives: Thromboxane A₂ synthase inhibition and thromboxane A₂ receptor antagonism combined in one molecule

Doi:10.1021/jm00063a011
(1993)
Cooperative ruthenium complex catalyzed multicomponent synthesis of pyrimidines

Doi:10.1039/c9dt04040d
(2019)
REGIOSELECTIVE PALLADIUM(0) CATALYZED REDUCTION OF 1-ALKENYLCYCLOPROPYL ESTERS AS EQUIVALENT TO THE WITTIG REACTION

Doi:10.1016/S0040-4039(00)92074-4
(1992)
Stereocontrolled Synthesis of R or S, E or Z Unsaturated α-Amino Acids by Enantio- and Diastereoselective Epoxidation of δ-Hydroxy Allylic Phosphine Oxides

Doi:10.1016/S0040-4039(00)91787-8
(1993)

Article Doi