Dibenzoxepin derivatives: Thromboxane A2 synthase inhibition and thromboxane A2 receptor antagonism combined in one molecule

DOI: 10.1021/jm00063a011

Source and publish data:

Journal of Medicinal Chemistry p. 1613 - 1618 (1993)

Update date:2022-08-03

Topics:

Authors:

Ohshima Ohshima

Sato Sato

Obase Obase

Miki Miki

Ishii Ishii

Kawakage

Shirakura

Karasawa

Kubo Kubo

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00063a011

A new series of 6,11-dihydrodibenz[b,e]oxepin derivatives exerting both thromboxane synthase inhibitory (TXS-I) and thromboxane receptor antagonist (TXRA) activities is described. (-)-11-[(3-Pyridylmethyl)thio]-6,11- dihydrodibenz[b,e]oxepin-2-carboxylic

Full text of DOI:10.1021/jm00063a011

Products guided by the article

Product name:11-Benzylamino-6,11-dihydro-dibenzo[b,e]oxepine-2-carboxylic acid methyl ester

Cas No:148216-24-4

R&D Labs maybe for 148216-24-4

Zhejiang Haizhou Pharmaceutical Co., Ltd.

website:https://www.haizhoupharma.com/

Contact:+86-576-88221016

Address:No. 19, Donghai 5th Avenue, Yanhai Industrial Zone, Linhai, Zhejiang, China
Shandong Jiulong Hisince Pharmaceutical Co.,Ltd.

Contact:+86-15853188990

Address:Huadian Pioneer Park, Huadian Township, Qihe County, Dezhou City, Shandong, P.R.China
zhejiang huangyan wanfeng pharm chem co.ltd

Contact:+86-576- 84160728

Address:No. 5 Dazha Road, Economic,Development Zone(JiangKou), Zhejiang, China
BAODING SINO-CHEM INDUSTRY CO.,LTD

Contact:0312-5956088

Address:NO.8 FUXING ROAD,CHINA
QINGDAO NEW FLOURISH INTERNATIOANAL TRADE CO., LTD.

Contact:+86 532 80861829

Address:No. 1, Yinchuan East Road, 266061, Qingdao, China

Relevant to this article

Reaction of electrophiles with manganese(I) and rhenium(I) alkoxide complexes: Reversible absorption of atmospheric carbon dioxide

Doi:10.1021/om00029a032
(1993)
Doi:10.1039/jr9470000433
()
Synthesis and pharmacological evaluation of 5,6,7,8-tetrahydro-6-amino>-1,2-naphthalenediol: a novel non-selective dopamine-receptor agonist

Doi:10.1002/recl.19931120211
(1993)
Doi:10.1039/J19700002922
()
Antibody catalyzed hydrolysis of enol ethers

Doi:10.1021/ja00063a009
(1993)
Hydride, chloride, and bromide show similar electronic effects in the Au₉(PPh₃)₈³⁺ nanocluster

Doi:10.1039/c9cc08009k
(2020)

Article Doi