Dibenzoxepin derivatives: Thromboxane A2 synthase inhibition and thromboxane A2 receptor antagonism combined in one molecule

DOI: 10.1021/jm00063a011

Source and publish data:

Journal of Medicinal Chemistry p. 1613 - 1618 (1993)

Update date:2022-08-03

Topics:

Authors:

Ohshima Ohshima

Sato Sato

Obase Obase

Miki Miki

Ishii Ishii

Kawakage

Shirakura

Karasawa

Kubo Kubo

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00063a011

A new series of 6,11-dihydrodibenz[b,e]oxepin derivatives exerting both thromboxane synthase inhibitory (TXS-I) and thromboxane receptor antagonist (TXRA) activities is described. (-)-11-[(3-Pyridylmethyl)thio]-6,11- dihydrodibenz[b,e]oxepin-2-carboxylic

Full text of DOI:10.1021/jm00063a011

Products guided by the article

Product name:11-Benzylamino-6,11-dihydro-dibenzo[b,e]oxepine-2-carboxylic acid methyl ester

Cas No:148216-24-4

R&D Labs maybe for 148216-24-4

Hangzhou Share Chemical Co., Ltd(expird)

Contact:+86-57187093700

Address:Hang Xing Road
Chongqing Werlchem Fine Chemical Co. Ltd

Contact:+86-23-67521957

Address:NO.15,Fortune Road,Yubei District,401121,Chongqing,China
Shanghai Hanshare Industry Co.,Ltd.

Contact:86 21 20960688

Address:RM902-903,Building E, Wanda Plaza,No.26,Zhoukang Road, Pudong District, Shanghai, China
Zibo Jujin Chemical Industry Co., Ltd.（Dongming Jujin Chemical Industry Co., Ltd. ）

Contact:+86-533-2975022

Address:No.99 Shanquan Road, Zhangdian District
LIAONING DMSO CHEMICALS CO.,LTD.

website:http://www.chinadmso.com

Contact:+86-427-6503033

Address:FLOOR 16, BLOCK A, FINANCIAL SQUARE, XINGLONGTAI DISTRICT, PANJIN CITY, LIAONING P.R. CHINA

Relevant to this article

Reaction of electrophiles with manganese(I) and rhenium(I) alkoxide complexes: Reversible absorption of atmospheric carbon dioxide

Doi:10.1021/om00029a032
(1993)
Doi:10.1039/jr9470000433
()
Synthesis and pharmacological evaluation of 5,6,7,8-tetrahydro-6-amino>-1,2-naphthalenediol: a novel non-selective dopamine-receptor agonist

Doi:10.1002/recl.19931120211
(1993)
Doi:10.1039/J19700002922
()
Antibody catalyzed hydrolysis of enol ethers

Doi:10.1021/ja00063a009
(1993)
Hydride, chloride, and bromide show similar electronic effects in the Au₉(PPh₃)₈³⁺ nanocluster

Doi:10.1039/c9cc08009k
(2020)

Article Doi