Chemical and Pharmaceutical Bulletin p. 3214 - 3221 (1992)
Update date:2022-08-03
Topics:
Atsuumi
Nakano
Koike
Tanaka
Funabashi
Matsuyama
Nakano
Sawasaki
Funabashi
Morishima
The synthesis and structure-activity relationships of N-terminus modified renin inhibitors containing the homostatine analogue, (2RS,4S,5S)-5-amino-2-ethyl-4-hydroxy-7-methyloctanoic acid, are described. The compounds having a 3-alkyl (or aryl)sulfonylpro
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