Journal of Antibiotics p. 478 - 484 (1996)
Update date:2022-08-04
Topics:
Iso
Irie
Iwaki
Kii
Sendo
Motokawa
Nishitani
We describe an efficient method for introducing a sulfamoylamino group into the C-2' position of pyrrolidine using the Mitsunobu reaction. S-4661, its N-methyl analogues and stereoisomers were synthesized using this method and their structure-activity relationships were investigated.
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