Chemistry of Heterocyclic Compounds p. 1179 - 1181 (1992)
Update date:2022-07-30
Topics:
Demina, L. M.
Konshin, M. E.
It is shown that on boiling 2-amino-4,6-dimethylnicotinic acid arylamides with triethyl orthoformate in acetic anhydride, derivatives of 3-aryl-5,7-dimethyl-4-oxo-3,4-dihydropyrido<2,3-d>pyrimidine are formed.The same compounds are obtained by ternary condensation of ethyl 2-amino-4,6-dimethylnicotinate with triethyl orthoformate and arylamines.On reaction with urea or ammonium thiocyanate, the ethyl ester or anilides of 2-amino-4,6-dimethylnicothinic acid are converted to 2,4-dioxo- or 4-oxo-2-thio-pyrido<2,3-d>pyrimidines respectively.
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Doi:10.1016/0008-6215(92)85037-Z
(1992)Doi:10.1007/s00706-013-1109-1
(2014)Doi:10.1016/S0040-4020(01)91222-0
(1993)Doi:10.1080/17415993.2013.830726
(2014)Doi:10.1016/j.dyepig.2020.108289
(2020)Doi:10.1016/0022-328X(93)83177-W
(1993)
