Journal of Medicinal Chemistry p. 1654 - 1661 (1993)
Update date:2022-07-29
Topics: Synthesis Tetrapeptide Modulation Physicochemical Properties Pharmacological Properties
Kucharczyk, Nathalie
Thurieau, Christophe
Paladino, Joseph
Morris, Angela D.
Bonnet, Jacqueline
et al.
We report on the synthesis and the pharmacological properties of a new series of tachykinin antagonists based on the pseudopeptide pharmacophore cyclo<-Abo-Asp(D-Trp-Phe-N(Me)Bzl)-> which contains the 2-azabicyclo<2.2.2>octane-3(S)-carboxylic acid (Abo) r
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Doi:10.1007/s10600-013-0766-y
(2013)Doi:10.1021/ja00974a014
(1966)Doi:10.1021/jo00071a024
(1993)Doi:10.1055/s-0036-1591576
(2018)Doi:10.3184/174751913X13736278296459
(2013)Doi:10.1007/BF00912447
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