Total synthesis of the macrolide antibiotic rutamycin B

DOI: 10.1021/ja00077a049

Source and publish data:

Journal of the American Chemical Society p. 11446 - 11459 (1993)

Update date:2022-08-05

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Authors:

Evans Evans

Rieger Rieger

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Article abstract of DOI:10.1021/ja00077a049

A convergent asymmetric synthesis of the macrolide antibiotic rutamycin B has been achieved through the synthesis and coupling of its spiroketal and polypropionate subunits. Both fragments were constructed utilizing auxiliary based asymmetric aldol and al

Full text of DOI:10.1021/ja00077a049

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