
Journal of the American Chemical Society p. 11446 - 11459 (1993)
Update date:2022-08-05
Topics:
Evans
Ng
Rieger
A convergent asymmetric synthesis of the macrolide antibiotic rutamycin B has been achieved through the synthesis and coupling of its spiroketal and polypropionate subunits. Both fragments were constructed utilizing auxiliary based asymmetric aldol and al
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Doi:10.1039/j39660002349
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(1993)