FLUORINATED ANALOGS OF INS(1,4,5)P3

DOI: 10.1016/S0040-4039(01)80578-5

Source and publish data:

Tetrahedron Letters p. 5401 - 5404 (1989)

Update date:2022-09-26

Topics:

Authors:

Marecek, James F.

Prestwich, Glenn D.

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Article abstract of DOI:10.1016/S0040-4039(01)80578-5

2-Fuoro-2-deoxy-Ins(1,4,5)P₃ (2) and 2,2-difluoro-2-deoxy-Ins(1,4,5)P₃ (3) were synthesized from protected inositol precursors.The monofluoro compound with free 3,6-hydroxyl groups underwent slow defluorination at pH > 13, as determi

Full text of DOI:10.1016/S0040-4039(01)80578-5

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