Chemoenzymatic synthesis of optically active 1,4-dihydroxypyridine derivatives via enantioselective hydrolysis and transesterification

DOI: 10.1016/S0957-4166(00)82255-7

Source and publish data:

Tetrahedron Asymmetry p. 2061 - 2068 (1993)

Update date:2022-07-30

Topics:

Authors:

Adachi Adachi

Ishii Ishii

Ohta Ohta

Ota Ota

Ogawa Ogawa

Hanada Hanada

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Article abstract of DOI:10.1016/S0957-4166(00)82255-7

(4R)-(-)-2-(Nicotinoylamino)ethyl-3-nitrooxypropyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3,5-pyridinedicarboxylate (1), a new calcium antagonist, was synthesized via both enantioselective hydrolysis and transesterification of prochiral bis[2-(nicotin

Full text of DOI:10.1016/S0957-4166(00)82255-7

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Product name:(4R)-(-)-3-<2-(nicotinoylamino)ethoxycarbonyl>-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-5-carboxylic acid

Cas No:149416-66-0

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