Synthesis of possible metabolites of 1-cyclopropyl-1,4-dihydro-6-fluoro- 5-methyl-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid (grepafloxacin, OPC-17116)

DOI: 10.1248/cpb.43.2246

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 2246 - 2252 (1995)

Update date:2022-08-03

Topics:

Authors:

Morita Morita

Otsubo Otsubo

Matsubara

Ohtani Ohtani

Kawano Kawano

Ohmori Ohmori

Ohguro Ohguro

Uchida Uchida

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.43.2246

Grepafloxacin (1-cyclopropyl-1,4-dihydro-6-fluoro-5-methyl-7-(3-methyl-1- piperazinyl)-4-oxo-3-quinoline-carboxylic acid, OPC-17116) (1) exhibits potent and broad-spectrum in vitro and in vivo antibacterial activity. In order to identify the structures of

Full text of DOI:10.1248/cpb.43.2246

NII-Electronic Library Service

Products guided by the article

Product name:7-(2-tert-Butoxycarbonylamino-ethylamino)-1-cyclopropyl-6-fluoro-5-methyl-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid

Cas No:149602-53-9

R&D Labs maybe for 149602-53-9

Zhejiang Haizhou Pharmaceutical Co., Ltd.

website:https://www.haizhoupharma.com/

Contact:+86-576-88221016

Address:No. 19, Donghai 5th Avenue, Yanhai Industrial Zone, Linhai, Zhejiang, China
Anhui Redstar Pharmaceutical Corp., Ltd

Contact:+86-563-5120837

Address:Jingxian Industrial Development Zone, Anhui , China
Jiangsu Institute of Ecomones Co., Ltd

website:http://www.jsmone.com

Contact:+86-519-82821700

Address:95 Huanyuan N. Road, Jintan, Jiangsu, China
feixia327@163.com

Contact:--

Address:80G, No.1 Building, Guodu Development Mansion, No. 182 Zhaohui Road, Hangzhou City, Zhejiang Province,China.
NOVASYNCS CO., LTD

Contact:0512-63006287

Address:no.88.YISHENG Road,etdz-WUJIANG,SUZHOU,CHINA

Relevant to this article

Doi:10.1002/zaac.19673490510
(1967)
Rate of interconversion of syn and anti rotamers of Mo(CHCMe₂Ph)(NAr)(OR)₂ and relative reactivity toward 2,3-bis(trifluoromethyl)norbornadiene

Doi:10.1021/ja00045a056
(1992)
Insights into the Mechanism of Thiol-Triggered COS/H₂S Release from N-Dithiasuccinoyl Amines

Doi:10.1021/acs.joc.0c00559
(2020)
Kinetics and mechanism of the liquid-phase reaction of 2,4-dinitrotoluene with ozone in the presence of manganese(II) acetate

Doi:10.1134/S0023158413060050
(2013)
FREE RADICAL CHAIN REACTIONS OF 3-FLUORO-3-IODO-β-LACTAMS

Doi:10.1016/S0040-4039(00)93386-0
(1993)
Synthesis, crystal structures, and biological evaluation of Cu(II) and Zn(II) complexes of 2-benzoylpyridine Schiff bases derived from S-methyl- and S-phenyldithiocarbazates

Doi:10.1016/j.jinorgbio.2011.09.034
(2012)

Article Doi